Research Associate/Sr. Research Associate, Discovery Biology


Silverback Therapeutics, a Seattle-based biopharmaceutical company, is seeking a highly motivated individual to join our Discovery Biology team and contribute to the development of innovative immune-modulating therapeutics.  Applicants should be comfortable in a fast-paced and highly collaborative environment.

Key Responsibilities:

  • Hands-on research activities contribute to the discovery, validation, and development of Silverback’s portfolio of therapeutics.
  • Perform studies to assess therapeutic efficacy and mechanism of action using a variety of in vivo immuno-oncology and fibrosis models utilizing hands-on techniques in vivarium.
  • Work collaboratively within a multidisciplinary team.


  • BS or MS degree in biological sciences, or a related degree with 3-5 years of research experience.


Hands-on in vivo experience, particularly in the areas of conducting syngeneic and xenograft tumor models and/or mouse models of fibrosis. Experience performing ELISAs, flow cytometry, and mammalian tissue culture is desired but not required. Ability to work in a fast-paced team environment, meet deadlines, and prioritize work on multiple projects. Strong organization, time management, and problem-solving skills, with attention to detail.  Exposure to drug development in the therapeutic areas of immunology, and/or fibrosis is preferred but not required.

Silverback Therapeutics is a privately held biopharmaceutical company advancing a pipeline of therapies that are systemically delivered, but locally active and target fundamental disease pathways. Silverback’s ImmunoTAC™ platform enables innovative therapeutic approaches to oncology, virology and fibrotic diseases. Silverback’s lead candidate, SBT6050, is comprised of a potent TLR8 agonist conjugated to a HER2-directed monoclonal antibody, designed for systemic delivery with tumor-localized activation of myeloid cells. Clinical investigation of SBT6050 is expected to begin in 2020. Silverback was founded in 2016. To learn more, visit We offer our employees competitive compensation and benefits, including paid time off, health insurance, life insurance, flexible spending accounts, a 401(k) plan, and stock options. Qualified candidates should forward their resumes to We are an equal opportunity employer.